The CNGA3 Polyclonal Antibody (CAB3288) is specifically designed for researchers studying CNGA3, a key protein involved in the function of cyclic nucleotide-gated ion channels. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.CNGA3 is known to play a crucial role in various physiological processes, including sensory transduction in vision and olfaction. By targeting the CNGA3 protein, this antibody enables researchers to detect and analyze its expression in different cell types, providing valuable insights for studies in neuroscience and sensory biology.
Understanding the function of CNGA3 is essential for unraveling its role in sensory perception and potential implications in disorders such as retinal degeneration and olfactory dysfunction. This antibody serves as a powerful tool for investigating the molecular mechanisms underlying these conditions and advancing research in the field of sensory physiology.
Product Name:
CNGA3 Rabbit Polyclonal Antibody
SKU:
CAB3288
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human CNGA3 (NP_001289.1).
This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
1261
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CNGA3 antibody (CAB3288) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
