CMTM7 Antibody (PACO17940)
- SKU:
- PACO17940
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
CMTM7 Antibody (PACO17940)
The CMTM7 Polyclonal Antibody (PAC017940) is a valuable tool for researchers studying CMTM7, a protein involved in immune regulation and cancer development. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CMTM7 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in immunology and oncology research.
CMTM7, known as a potential tumor suppressor, is thought to play a role in regulating cell growth and proliferation. Research into the function of CMTM7 is critical for understanding its impact on cancer progression and identifying potential therapeutic targets. By utilizing the CMTM7 Polyclonal Antibody, researchers can further explore the role of CMTM7 in cancer biology and potentially uncover new insights into the development and treatment of cancer.
| Antibody Name: | CMTM7 Antibody (PACO17940) |
| Antibody SKU: | PACO17940 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human CMTM7 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17940(CMTM7 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO17940(CMTM7 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Synonyms: | CKLF-like MARVEL transmembrane domain containing 7 |
| UniProt Protein Function: | CMTM7: a member of the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Cytokine; Membrane protein, integral; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 3p22.3 Cellular Component: membrane |
| NCBI Summary: | This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1/S transition in the cell cycle, and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] |
| UniProt Code: | Q96FZ5 |
| NCBI GenInfo Identifier: | 34922026 |
| NCBI Gene ID: | 112616 |
| NCBI Accession: | Q96FZ5.1 |
| UniProt Secondary Accession: | Q96FZ5,Q5VLK1, |
| UniProt Related Accession: | Q96FZ5 |
| Molecular Weight: | 15,452 Da |
| NCBI Full Name: | CKLF-like MARVEL transmembrane domain-containing protein 7 |
| NCBI Synonym Full Names: | CKLF like MARVEL transmembrane domain containing 7 |
| NCBI Official Symbol: | CMTM7Â Â |
| NCBI Official Synonym Symbols: | CKLFSF7Â Â |
| NCBI Protein Information: | CKLF-like MARVEL transmembrane domain-containing protein 7 |
| UniProt Protein Name: | CKLF-like MARVEL transmembrane domain-containing protein 7 |
| UniProt Synonym Protein Names: | Chemokine-like factor superfamily member 7 |
| Protein Family: | CKLF-like MARVEL transmembrane domain-containing protein |
| UniProt Gene Name: | CMTM7Â Â |
| UniProt Entry Name: | CKLF7_HUMAN |
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