The CMTM5 Polyclonal Antibody (PAC017941) is a valuable tool for research involving CMTM5, a member of the chemokine-like factor superfamily that plays important roles in immune regulation and cancer progression. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CMTM5 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential reagent for studies in immunology and oncology research.
CMTM5 is a key player in immune response modulation and has been implicated in the development and progression of various cancers. Its involvement in immune regulation and tumor growth makes it a promising target for further investigation in the fields of cancer biology and immunotherapy. Research into the functions of CMTM5 is essential for advancing our understanding of cancer biology and developing new therapeutic strategies for cancer treatment.
Antibody Name:
CMTM5 Antibody (PACO17941)
Antibody SKU:
PACO17941
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human CMTM5
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO17941(CMTM5 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene belongs to the chemokine-like factor gene superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. Highly expressed in the brain.
CMTM5: a member of the chemokine-like factor gene superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
UniProt Protein Details:
Protein type:Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: extracellular space; integral to membrane
Molecular Function:cytokine activity
Biological Process: negative regulation of myoblast differentiation; chemotaxis
NCBI Summary:
This gene encodes a member of the chemokine-like factor superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. The encoded protein may exhibit tumor suppressor activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
