The CMTM2 Antibody (PAC02272) is a vital tool for researchers studying the CMTM2 protein, a potential tumor suppressor involved in various cellular processes, including immune regulation and cancer development. This polyclonal antibody, generated in rabbits, exhibits high specificity and sensitivity when detecting CMTM2 in human samples, making it ideal for Western blot applications.CMTM2, also known as CKLF-like MARVEL transmembrane domain-containing protein 2, is a promising target for cancer research due to its ability to inhibit cell proliferation and promote apoptosis.
Understanding the function and regulation of CMTM2 can provide insights into the mechanisms underlying tumor growth and progression, offering potential therapeutic strategies for combating cancer.By utilizing the CMTM2 Antibody (PAC02272), researchers can investigate the role of CMTM2 in cancer biology and immune modulation, shedding light on its potential as a diagnostic biomarker or therapeutic target. This antibody enables precise detection and analysis of CMTM2 in a variety of cell types, contributing to advancements in oncology research and drug development efforts.
Antibody Name:
CMTM2 Antibody (PACO22272)
Antibody SKU:
PACO22272
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human CKLF2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, using CKLF2 antibody.
Background:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development.
CMTM2: a member of the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. [provided by RefSeq, Jul 2008]
UniProt Protein Details:
Protein type:Membrane protein, integral; Nuclear receptor co-regulator; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16q21
Cellular Component: nucleoplasm; extracellular space; integral to membrane
Molecular Function:cytokine activity
Biological Process: chemotaxis
NCBI Summary:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. [provided by RefSeq, Jul 2008]
