The CMTM2 Polyclonal Antibody (PAC014251) is a valuable tool for researchers studying the CMTM2 protein, a key player in regulating immune responses and cell proliferation. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding specifically to the CMTM2 protein, researchers can detect and analyze its expression in various cell types, making it ideal for investigations in immunology and cancer research.CMTM2 is involved in modulating immune responses and cell growth, making it a potential target for therapies aimed at manipulating immune function in diseases such as cancer and autoimmune disorders.
Understanding the role of CMTM2 in these contexts is essential for the development of new treatment strategies. Researchers can use this antibody to explore the functions of CMTM2 and its potential implications in various diseases, paving the way for new advances in immunotherapy and cancer research.
Antibody Name:
CMTM2 Antibody (PACO14251)
Antibody SKU:
PACO14251
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Fusion protein of human CMTM2
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO14251(CMTM2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14251(CMTM2 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development.
CMTM2: a member of the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. [provided by RefSeq, Jul 2008]
UniProt Protein Details:
Protein type:Membrane protein, integral; Nuclear receptor co-regulator; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 16q21
Cellular Component: nucleoplasm; extracellular space; integral to membrane
Molecular Function:cytokine activity
Biological Process: chemotaxis
NCBI Summary:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. [provided by RefSeq, Jul 2008]
