The CMTM1 Polyclonal Antibody (PAC017706) is specifically designed for research involving CMTM1, a crucial protein involved in immune regulation and cancer development. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in various applications, including Western blotting.CMTM1 is known for its role in modulating immune responses and has been linked to cancer progression. By binding to the CMTM1 protein, this antibody enables accurate detection and analysis of CMTM1 in different cell types, making it an ideal tool for researchers in the fields of immunology and oncology.
The importance of CMTM1 in immune system regulation and cancer development makes it a promising target for further investigation. Understanding the functions of CMTM1 could lead to insights into novel therapeutic approaches for cancer and other diseases related to immune dysfunction. By utilizing the CMTM1 Polyclonal Antibody, researchers can advance their studies and contribute to the development of potential treatments in these areas.
Antibody Name:
CMTM1 Antibody (PACO17706)
Antibody SKU:
PACO17706
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:500-1:5000, IHC:1:10-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human CMTM1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human urinary bladder tissue using PACO17706(CMTM1 Antibody) at dilution 1/10, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).
Synonyms:
CKLF-like MARVEL transmembrane domain-containing protein 1
UniProt Protein Function:
CMTM1: a member of the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CKLF (chemokine-like factor).[provided by RefSeq, Feb 2011]Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 16q21Cellular Component: extracellular space; integral to membraneMolecular Function: cytokine activityBiological Process: chemotaxis
