The UMP-CMP Kinase Polyclonal Antibody (CAB6561) is a valuable tool for researchers studying UMP-CMP kinase, an essential enzyme involved in nucleotide metabolism. This antibody is produced in rabbits and has been validated for use in Western blot applications with human samples. By targeting the UMP-CMP kinase protein, this antibody allows for the detection and analysis of this enzyme in various cell types, making it an ideal choice for studies in biochemistry and molecular biology.UMP-CMP kinase plays a crucial role in the synthesis of pyrimidine nucleotides, which are essential building blocks for DNA and RNA.
Dysregulation of this enzyme has been linked to various diseases, including cancer and genetic disorders. Therefore, understanding the function of UMP-CMP kinase is essential for developing potential therapies targeting nucleotide metabolism pathways.Overall, the UMP-CMP Kinase Polyclonal Antibody (CAB6561) is a powerful tool for researchers looking to further explore the role of UMP-CMP kinase in cellular processes and disease mechanisms. Its high reactivity and specificity make it a reliable choice for a wide range of experimental applications.
Product Name:
CMPK1 Rabbit Polyclonal Antibody
SKU:
CAB6561
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 69-228 of human CMPK1 (NP_057392.1).
WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
CK; CMK; UMK; CMPK; UMPK; UMP-CMPK; CMPK1
Positive Sample:
293T,HL-60,HT-29,HeLa,Mouse brain,Mouse kidney
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
22kDa
Observed MW:
22kDa
This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants.
Purification Method:
Affinity purification
Gene ID:
51727
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CMPK1 Rabbit pAb (CAB6561) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
