The CMKLR1 Polyclonal Antibody (CAB16358) is a valuable tool for researchers studying CMKLR1, a chemokine-like receptor 1 involved in immune cell recruitment and inflammation modulation. This antibody, generated in rabbits, demonstrates high specificity for human samples and has been validated for use in Western blot applications. By targeting the CMKLR1 protein, this antibody enables the detection and analysis of CMKLR1 expression in various cell types, making it an ideal choice for studies in immunology and inflammatory diseases.CMKLR1, also known as chemerin receptor 23, is a key player in immune response regulation, influencing leukocyte migration and cytokine production.
Its role in inflammation and its potential as a therapeutic target in diseases such as rheumatoid arthritis, inflammatory bowel disease, and atherosclerosis make it a compelling subject for research. Understanding the function and signaling pathways of CMKLR1 is essential for developing effective treatments that manipulate immune responses for therapeutic purposes.Overall, the CMKLR1 Polyclonal Antibody (CAB16358) offers researchers a valuable tool for investigating the role of CMKLR1 in immune system regulation and inflammatory processes, potentially leading to new insights and advancements in the field of immunology.
Product Name:
CMKLR1 Rabbit Polyclonal Antibody
SKU:
CAB16358
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CMKLR1 (NP_001135815.1).
Enables adipokinetic hormone binding activity and adipokinetic hormone receptor activity. Involved in several processes, including negative regulation of NF-kappaB transcription factor activity; positive regulation of macrophage chemotaxis; and regulation of calcium-mediated signaling. Located in plasma membrane.
Purification Method:
Affinity purification
Gene ID:
1240
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CMKLR1 Rabbit pAb (CAB16358) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
