The CMC4 Polyclonal Antibody (PAC016711) is a valuable tool for researchers studying the CMC4 protein, a critical component in mitochondrial biogenesis. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the CMC4 protein, this antibody enables detection and analysis in various cell types, making it ideal for research in biochemistry and cell biology.
The CMC4 protein plays a crucial role in maintaining the function and integrity of mitochondria, the powerhouse of the cell. Dysregulation of mitochondrial biogenesis has been associated with a variety of diseases, including neurodegenerative disorders and metabolic conditions. By studying the activity of CMC4, researchers can gain insight into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.
Antibody Name:
CMC4 Antibody (PACO16711)
Antibody SKU:
PACO16711
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human CMC4
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO16711(CMC4 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16711(CMC4 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the downstream 8 kDa protein that localizes to mitochondria.
Synonyms:
C-x(9)-C motif containing 4
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the downstream 8 kDa protein that localizes to mitochondria.[provided by RefSeq, Mar 2009]
