The CMAS Polyclonal Antibody (CAB13752) is specially designed for researchers studying CMAS, a critical enzyme involved in the synthesis of sialic acid, a key component of glycans on cell surfaces. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the CMAS protein, this antibody enables precise detection and analysis in various cell types, making it an essential tool for studies in glycobiology and cancer research.CMAS plays a crucial role in the biosynthesis of sialic acid, which is essential for cell-cell interactions, signaling, and immune responses.
Dysregulation of sialic acid metabolism has been implicated in various diseases, including cancer and neurological disorders. Therefore, understanding the function of CMAS is essential for unraveling the molecular mechanisms underlying these pathological conditions and developing potential therapeutic interventions targeting sialylation pathways.Overall, the CMAS Polyclonal Antibody (CAB13752) provides researchers with a valuable tool for investigating the role of CMAS in health and disease, shedding light on its potential as a target for novel therapeutic strategies in the fields of glycobiology, oncology, and neurobiology.
Product Name:
CMAS Rabbit Polyclonal Antibody
SKU:
CAB13752
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human CMAS (NP_061156.1).
This gene encodes an enzyme that converts N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc). This process is important in the formation of sialylated glycoprotein and glycolipids. This modification plays a role in cell-cell communications and immune responses. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55907
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CMAS Rabbit pAb (CAB13752) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
