Mast Cell Chymase (CMA1) Rabbit Polyclonal Antibody (CAB5668)
- SKU:
- CAB5668
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Mast Cell Chymase (CMA1) Rabbit Polyclonal Antibody |
SKU: | CAB5668 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 81-247 of human Mast Cell Chymase (CMA1) (NP_001827.1). |
Sequence: | ITEE EDTW QKLE VIKQ FRHP KYNT STLH HDIM LLKL KEKA SLTL AVGT LPFP SQFN FVPP GRMC RVAG WGRT GVLK PGSD TLQE VKLR LMDP QACS HFRD FDHN LQLC VGNP RKTK SAFK GDSG GPLL CAGV AQGI VSYG RSDA KPPA VFTR ISHY RPWI NQIL QAN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CYH; MCT1; chymase; Mast Cell Chymase (CMA1) |
Positive Sample: | A-549,A-431,HT-29,MCF7,Mouse lung,Mouse small intestine |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic granule, Secreted. |
Calculated MW: | 27kDa |
Observed MW: | 27kDa |
This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.
Purification Method: | Affinity purification |
Gene ID: | 1215 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |