The CLU Polyclonal Antibody (CAB13479) is specifically designed for research involving Clusterin (CLU), a protein that plays a key role in various cellular processes, including cell adhesion, apoptosis, and inflammation regulation. This antibody, raised in rabbits, is highly sensitive and specific to human samples, making it ideal for use in various applications such as Western blotting and immunohistochemistry.Clusterin, also known as apolipoprotein J, is a versatile protein that has been implicated in several disease processes, including cancer, neurodegenerative disorders, and cardiovascular diseases.
Studies have shown that Clusterin levels are dysregulated in many pathological conditions, making it a promising target for therapeutic intervention.With the CLU Polyclonal Antibody, researchers can effectively detect and analyze Clusterin expression in different cell types and tissues, allowing for a better understanding of its role in disease progression and potential therapeutic strategies. This antibody is a valuable tool for investigating the complex functions of Clusterin in various biological pathways, making it an essential component in cancer research, neurology, and cardiovascular studies.
Product Name:
CLU Rabbit Polyclonal Antibody
SKU:
CAB13479
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-449 of human Clusterin alpha chain (NP_976084.1).
The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.
Purification Method:
Affinity purification
Gene ID:
1191
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Clusterin Rabbit pAb (CAB13479) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
