The CLU Polyclonal Antibody (CAB12913) is a valuable tool for researchers studying Clusterin (CLU), a versatile glycoprotein involved in various physiological processes. This highly reactive antibody, produced in rabbits, is specifically designed for use in detecting CLU in human samples through Western blot applications. By binding to the CLU protein, this antibody enables researchers to analyze and track CLU expression in different cell types.CLU, also known as apolipoprotein J, is a multifunctional protein with roles in cell apoptosis, lipid metabolism, and protein folding. Its involvement in processes like cell differentiation and tissue remodeling makes it a key player in various diseases, including cancer, Alzheimer's disease, and cardiovascular disorders.
Research into the mechanisms of CLU function can provide crucial insights into disease pathogenesis and potential therapeutic targets.Overall, the CLU Polyclonal Antibody (CAB12913) is an essential tool for researchers interested in unraveling the complex functions of CLU and its implications in health and disease. Its high reactivity and specificity make it an ideal choice for studies in molecular biology, biochemistry, and biomedical research.
Product Name:
CLU Rabbit Polyclonal Antibody
SKU:
CAB12913
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 314-449 of human Clusterin alpha chain (NP_001822.3).
The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.
Purification Method:
Affinity purification
Gene ID:
1191
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Clusterin alpha chain Rabbit pAb (CAB12913) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
