Clathrin heavy chain Rabbit Polyclonal Antibody (CAB12423)
The CLTC Polyclonal Antibody (CAB12423) is a valuable tool for researchers studying CLTC, a key protein involved in the process of clathrin-mediated endocytosis. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the CLTC protein, it enables the detection and analysis of this critical component in various cell types, making it essential for studies in cell biology and molecular biology.CLTC is essential for the formation of clathrin-coated pits, which are crucial for the internalization of various cell surface receptors and molecules.
Dysregulation of CLTC has been implicated in diseases such as cancer and neurodegenerative disorders, making it an important target for research. Understanding the function of CLTC is essential for unraveling the mechanisms of endocytosis and its implications for disease progression.The CLTC Polyclonal Antibody (CAB12423) provides researchers with a reliable tool for exploring the role of CLTC in cellular processes and disease pathways. Its specificity and sensitivity make it an ideal choice for studying the function of this critical protein in a variety of experimental settings.
Product Name:
Clathrin heavy chain Rabbit Polyclonal Antibody
SKU:
CAB12423
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1451-1675 of human Clathrin heavy chain (NP_004850.1).
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.
Purification Method:
Affinity purification
Gene ID:
1213
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Clathrin heavy chain Rabbit pAb (CAB12423) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
