The CLTB Polyclonal Antibody (CAB8404) is a valuable tool for researchers studying CLTB, a protein involved in intracellular trafficking and membrane dynamics. This antibody, produced in rabbits, has been validated for use in Western blot applications and demonstrates high reactivity with human samples.CLTB plays a crucial role in facilitating the transport of vesicles within the cell and is essential for maintaining proper cellular function. By targeting the CLTB protein, researchers can investigate its involvement in various cellular processes such as endocytosis, membrane recycling, and organelle biogenesis.
Studies have shown that dysregulation of CLTB expression can lead to disruptions in cellular trafficking pathways, which may contribute to the development of diseases such as neurodegenerative disorders and cancer. By utilizing the CLTB Polyclonal Antibody, researchers can gain insights into the role of CLTB in these pathological conditions and potentially identify novel therapeutic targets for intervention.
Product Name:
CLTB Rabbit Polyclonal Antibody
SKU:
CAB8404
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human CLTB (NP_001825.1).
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1212
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CLTB antibody (CAB8404) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
