The CLTA Polyclonal Antibody (CAB3793) is specifically designed for research involving CLTA, a key protein involved in the process of clathrin-mediated endocytosis. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting. By binding to the CLTA protein, this antibody enables researchers to detect and analyze the role of CLTA in cellular processes in a wide range of cell types.CLTA is essential for the formation of clathrin-coated vesicles, which play a crucial role in the internalization of cell surface receptors and the regulation of various signaling pathways.
Understanding the function of CLTA is important for studying processes such as receptor trafficking, signal transduction, and endocytosis. This antibody provides a valuable tool for researchers investigating these mechanisms in fields such as cell biology, neuroscience, and drug discovery.
Product Name:
CLTA Rabbit Polyclonal Antibody
SKU:
CAB3793
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human CLTA (NP_001824.1).
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12.
Purification Method:
Affinity purification
Gene ID:
1211
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CLTA antibody (CAB3793) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
