The CLSTN3 Polyclonal Antibody (CAB15765) is a valuable tool for researchers studying CLSTN3, a cell surface protein that plays a key role in synaptic transmission and neurodevelopment. This antibody, produced in rabbits, is highly specific to human CLSTN3 and has been validated for use in Western blot applications. By targeting the CLSTN3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in neuroscience and neurodegenerative diseases.CLSTN3, also known as calsyntenin 3, is essential for proper synaptic function and neuronal connectivity in the brain.
Dysregulation of CLSTN3 has been implicated in various neurological disorders, including Alzheimer's disease and schizophrenia. Research into the function of CLSTN3 is crucial for understanding the mechanisms underlying these disorders and developing targeted treatment strategies.Overall, the CLSTN3 Polyclonal Antibody (CAB15765) provides researchers with a powerful tool for investigating the role of CLSTN3 in synaptic plasticity and neurological diseases, paving the way for advancements in our understanding of the brain and potential avenues for therapeutic intervention.
Product Name:
CLSTN3 Rabbit Polyclonal Antibody
SKU:
CAB15765
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 730-850 of human CLSTN3 (NP_055533.2).
Sequence:
SLQQ RGLE LTNT SAYL TIAG VESI TVYE EILR QARY RLRH GAAL YTRK FRLS CSEM NGRY SSNE FIVE VNVL HSMN RVAH PSHV LSSQ QFLH RGHQ PPPE MAGH SLAS SHRN SMIP SAAT L
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
CSTN3; CDHR14; alcbeta; CLSTN3
Positive Sample:
Mouse brain
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus membrane, Single-pass type I membrane protein.
Calculated MW:
106kDa
Observed MW:
105kDa
Predicted to enable calcium ion binding activity. Predicted to be involved in positive regulation of synapse assembly and positive regulation of synaptic transmission. Predicted to act upstream of or within several processes, including chemical synaptic transmission; positive regulation of protein localization to synapse; and synapse assembly. Predicted to be located in postsynaptic density. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynaptic membrane. Predicted to be integral component of postsynaptic density membrane.
Purification Method:
Affinity purification
Gene ID:
9746
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using CLSTN3 Rabbit pAb (CAB15765) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
