The CLRN3 Polyclonal Antibody (PAC037974) is a valuable tool for researchers studying CLRN3, a protein associated with various sensory functions and diseases of the nervous system. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blot applications. By targeting the CLRN3 protein, researchers can confidently analyze its expression in different cell types, making this antibody ideal for studies in neurobiology and neurodegenerative diseases.CLRN3, also known as clarin-3, is a protein that plays a crucial role in maintaining sensory function in the auditory and vestibular systems. Mutations in the CLRN3 gene have been linked to conditions such as Usher syndrome, a genetic disorder characterized by hearing loss and vision impairment.
Research into the function and regulation of CLRN3 is essential for understanding the underlying mechanisms of these diseases and potentially developing targeted therapies in the future.By using the CLRN3 Polyclonal Antibody (PAC037974), researchers can further investigate the role of CLRN3 in sensory function and disease pathology, advancing our knowledge of neurobiology and contributing to the development of innovative treatments for disorders affecting the auditory and visual systems.
Immunofluorescent analysis of Hela cells using PACO37974 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
extracellular exosome
Synonyms:
Clarin-3 (Transmembrane protein 12) (Usher syndrome type-3A-like protein 1), CLRN3, TMEM12 USH3AL1
UniProt Protein Function:
CLRN3: Belongs to the clarin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 10q26.2
