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CLPX Polyclonal Antibody (CAB17088)

SKU:
CAB17088
Product Type:
Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
€139 - €419
Frequently bought together:

Description

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Product Name:CLPX Polyclonal Antibody
SKU:CAB17088
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 500-600 of human CLPX (NP_006651.2).
Sequence:LPVV VPLH SLDE KTLV QILT EPRN AVIP QYQA LFSM DKCE LNVT EDAL KAIA RLAL ERKT GARG LRSI MEKL LLEP MFEV PNSD IVCV EVDK EVVE GKKE P
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:EPP2; CLPX
Positive Sample:Mouse liver,Rat live
Cellular Localization:cytosol, mitochondrial endopeptidase Clp complex, mitochondrial inner membrane, mitochondrial matrix, mitochondrial nucleoid, mitochondrion, nucleoplasm
Calculated MW:69kDa
Observed MW:69kDa

The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.

Purification Method:Affinity purification
Gene ID:10845
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using CLPX Rabbit pAb (CAB17088) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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