CLPS Rabbit Polyclonal Antibody (CAB12772)
- SKU:
- CAB12772
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CLPS Rabbit Polyclonal Antibody |
SKU: | CAB12772 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 13-112 of human CLPS (NP_001823.1). |
Sequence: | SVAY AAPG PRGI IINL ENGE LCMN SAQC KSNC CQHS SALG LARC TSMA SENS ECSV KTLY GIYY KCPC ERGL TCEG DKTI VGSI TNTN FGIC HDAG RSKQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CLPS; colipase |
Positive Sample: | Mouse pancreas,Rat pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 12kDa |
Observed MW: | 12kDa |
The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1208 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |