CLN8 Rabbit Polyclonal Antibody (CAB16843)
- SKU:
- CAB16843
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CLN8 Rabbit Polyclonal Antibody |
SKU: | CAB16843 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-286 of human CLN8 (NP_061764.2). |
Sequence: | MFHC RMVL TYHM WWVC FWHW DGLV SSLY LPHL TLFL VGLA LLTL IINP YWTH KKTQ QLLN PVDW NFAQ PEAK SRPE GNGQ LLRK KRP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:500 |
Synonyms: | EPMR; TLCD6; C8orf61; CLN8 |
Positive Sample: | SKOV3,LO2,HeLa,K-562 |
Cellular Localization: | endoplasmic reticulum, mitochondrion, presynapse |
Calculated MW: | 33kDa |
Observed MW: | 33kDa |
This gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER-Golgi intermediate compartment. Mutations in this gene are associated with a disorder characterized by progressive epilepsy with cognitive disabilities (EPMR), which is a subtype of neuronal ceroid lipofuscinoses (NCL). Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain.
Purification Method: | Affinity purification |
Gene ID: | 2055 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |