CLN5 Rabbit Polyclonal Antibody (CAB12886)
- SKU:
- CAB12886
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CLN5 Rabbit Polyclonal Antibody |
SKU: | CAB12886 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 96-407 of human CLN5 (NP_006484.1). |
Sequence: | IPSR RHWP VPYK RFDF RPKP DPYC QAKY TFCP TGSP IPVM EGDD DIEV FRLQ APVW EFKY GDLL GHLK IMHD AIGF RSTL TGKN YTME WYEL FQLG NCTF PHLR PEMD APFW CNQG AACF FEGI DDVH WKEN GTLV QVAT ISGN MFNQ MAKW VKQD NETG IYYE TWNV KASP EKGA ETWF DSYD CSKF VLRT FNKL AEFG AEFK NIET NYTR IFLY SGEP TYLG NETS VFGP TGNK TLGL AIKR FYYP FKPH LPTK EFLL SLLQ IFDA VIVH KQFY LFYN FEYW FLPM KFPF IKIT YEEI PLPI RNKT LSGL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | CLN5; NCL |
Positive Sample: | Mouse heart,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome. |
Calculated MW: | 41kDa |
Observed MW: | 41kDa |
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.
Purification Method: | Affinity purification |
Gene ID: | 1203 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |