The CLIP1 Polyclonal Antibody (CAB12498) is a valuable tool for researchers studying CLIP1, a protein involved in microtubule dynamics and cell division. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding to the CLIP1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and cancer research.
CLIP1 plays a crucial role in regulating microtubule dynamics, which is essential for cell division and intracellular transport processes. Dysregulation of CLIP1 has been linked to abnormal cell division and tumor development, making it a potential target for cancer therapy research. By understanding the functions and mechanisms of CLIP1, researchers can gain insights into cell division processes and potential therapeutic strategies for cancer treatment.
Product Name:
CLIP1 Rabbit Polyclonal Antibody
SKU:
CAB12498
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1228-1427 of human CLIP1 (NP_002947.1).
The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6249
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CLIP1 antibody (CAB12498) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
