The CLIC6 Polyclonal Antibody (PACO4627) is a valuable tool for researchers studying the CLIC6 protein, a member of the chloride intracellular channel (CLIC) family implicated in various cellular processes. This antibody is produced in rabbits and shows high reactivity with human samples, making it suitable for use in Western blot applications. By specifically binding to the CLIC6 protein, this antibody enables researchers to detect and analyze its expression in different cell types, making it a valuable tool for studies in cell biology and molecular biology.
CLIC6 is known to play a role in regulating intracellular chloride transport and membrane dynamics, with implications in processes such as cell proliferation, migration, and cell cycle regulation. Research into the function of CLIC6 can provide valuable insights into cellular mechanisms and potential therapeutic targets for diseases linked to abnormal chloride transport. The CLIC6 Polyclonal Antibody is a reliable reagent for researchers looking to investigate the function of CLIC6 and its role in various cellular processes.
Antibody Name:
CLIC6 Antibody
Antibody SKU:
PACO04627
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human CLIC6.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
CLIC6; CLIC1L; Chloride intracellular channel protein 6; Parchorin
UniProt Protein Function:
CLIC6: May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport. Belongs to the chloride channel CLIC family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Channel, chloride; Membrane protein, integralChromosomal Location of Human Ortholog: 21q22.12Cellular Component: cytoplasm; nucleusMolecular Function: chloride channel activity; glutathione transferase activityBiological Process: glutathione metabolic process
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the chloride intracellular channel family of proteins. The gene is part of a large triplicated region found on chromosomes 1, 6, and 21. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2015]
