The Clic4 Polyclonal Antibody (CAB7088) is a vital tool for researchers studying the Clic4 protein, which plays a key role in regulating cell migration and invasion in cancer. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples. By targeting the Clic4 protein, researchers can accurately detect and analyze its expression in various cell types, making it ideal for studies in cancer biology and metastasis.Clic4, also known as chloride intracellular channel protein 4, is involved in controlling cell adhesion, motility, and invasion, making it a potential therapeutic target for inhibiting cancer progression and metastasis.
Understanding the mechanisms by which Clic4 functions can provide valuable insights into developing targeted therapies for cancer patients.Overall, the Clic4 Polyclonal Antibody (CAB7088) offers researchers a reliable tool for investigating the role of Clic4 in cancer biology and metastasis, ultimately contributing to the development of innovative treatment strategies for cancer patients.
Product Name:
CLIC4 Rabbit Polyclonal Antibody
SKU:
CAB7088
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human CLIC4 (NP_039234.1).
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
Purification Method:
Affinity purification
Gene ID:
25932
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CLIC4 Rabbit pAb (CAB7088) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
