The CLIC3 Polyclonal Antibody (CAB15347) is a valuable tool for researchers studying CLIC3, a protein involved in various cellular processes such as ion channel activity, cell proliferation, and apoptosis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically targeting the CLIC3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and cancer research.CLIC3, a member of the chloride intracellular channel protein family, plays a crucial role in regulating cellular functions and has been implicated in the development and progression of cancer.
Its diverse functions make it a promising target for investigating potential therapeutic strategies for cancer treatment. By gaining insights into the mechanisms by which CLIC3 operates, researchers can uncover new avenues for developing novel and effective anti-cancer therapies.Overall, the CLIC3 Polyclonal Antibody (CAB15347) is a reliable tool for researchers seeking to explore the role of CLIC3 in cellular processes and cancer biology. Its versatility and specificity make it a valuable asset in advancing our understanding of the complex mechanisms underlying cancer development and progression.
Product Name:
CLIC3 Rabbit Polyclonal Antibody
SKU:
CAB15347
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 87-236 of human CLIC3 (NP_004660.2).
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.
Purification Method:
Affinity purification
Gene ID:
9022
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CLIC3 Rabbit pAb (CAB15347) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
