The CLEC5A Polyclonal Antibody (CAB2873) is a vital tool for researchers studying CLEC5A, a C-type lectin receptor involved in immune responses and inflammation. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it suitable for various research applications, including Western blot analysis. By binding specifically to the CLEC5A protein, this antibody enables precise detection and analysis in different cell types, allowing for comprehensive studies in immunology and related fields.
CLEC5A plays a crucial role in immune signaling pathways and is known to be involved in the inflammatory response to viral and bacterial infections. By understanding the function of CLEC5A, researchers can gain insights into the mechanisms underlying immune activation and potentially develop targeted therapies for infectious diseases and inflammatory conditions. The CLEC5A Polyclonal Antibody is a valuable tool for investigating the role of this receptor in immune regulation and disease pathogenesis.
Product Name:
CLEC5A Rabbit Polyclonal Antibody
SKU:
CAB2873
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-188 of human CLEC5A (NP_037384.1).
Cell membrane, Single-pass type II membrane protein.
Calculated MW:
22kDa
Observed MW:
20kDa
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined.
Purification Method:
Affinity purification
Gene ID:
23601
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CLEC5A antibody (CAB2873) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
