The CLEC4A Polyclonal Antibody (CAB2713) is a valuable tool for research involving CLEC4A, a cell surface receptor with diverse functions in regulating immunity, inflammation, and homeostasis. Raised in rabbits, this antibody is highly specific for human samples and is validated for use in Western blot applications. By binding to the CLEC4A protein, it allows for the detection and analysis of this receptor in various cell types, making it suitable for a wide range of research areas including immunology, infectious diseases, and cancer.CLEC4A, also known as Dectin-2, is a member of the C-type lectin superfamily and has been implicated in the recognition of pathogens, modulation of immune responses, and maintenance of tissue integrity.
Its role in shaping the immune system's response to different stimuli makes it an attractive target for studying infectious diseases, autoimmune disorders, and inflammation-related conditions. Understanding the function and signaling pathways of CLEC4A is essential for developing novel therapeutic strategies that target this receptor for treating various diseases.In conclusion, the CLEC4A Polyclonal Antibody (CAB2713) is a reliable tool for researchers looking to investigate the role of CLEC4A in immune responses and disease pathogenesis. Its high specificity and sensitivity make it an invaluable asset in the study of this important cell surface receptor.
Product Name:
CLEC4A Rabbit Polyclonal Antibody
SKU:
CAB2713
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CLEC4A (Q9UMR7).
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Purification Method:
Affinity purification
Gene ID:
50856
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CLEC4A Rabbit pAb (CAB2713) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
