The CLEC1B Polyclonal Antibody (CAB9971) is a powerful tool for researchers studying CLEC1B, a C-type lectin receptor involved in immune regulation and inflammation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the CLEC1B protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential tool for studies in immunology and cancer research.
CLEC1B, a member of the C-type lectin family, plays a crucial role in immune response modulation by regulating immune cell activation and inflammation. Its involvement in these processes makes it a promising target for research into diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the function of CLEC1B is vital for developing therapeutic interventions that can modulate immune responses in these disease settings.
Product Name:
CLEC1B Rabbit Polyclonal Antibody
SKU:
CAB9971
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-196 of human CLEC1B (NP_001092901.1).
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).
Purification Method:
Affinity purification
Gene ID:
51266
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CLEC1B Rabbit pAb (CAB9971) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
