The CLEC10A Polyclonal Antibody (CAB11859) is a valuable tool for researchers studying CLEC10A, a type II transmembrane protein involved in the immune response. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. By binding to the CLEC10A protein, this antibody allows for the detection and analysis of CLEC10A in various cell types, making it an ideal choice for studies in immunology and infectious diseases research.CLEC10A, also known as dendritic cell immunoreceptor (DCIR), is a C-type lectin receptor expressed on dendritic cells and involved in immune regulation. It has been implicated in antigen uptake and presentation, as well as modulating immune signaling pathways.
Research into CLEC10A function is important for understanding how dendritic cells contribute to immune responses and for developing novel immunotherapies for infectious diseases and cancer.With its high specificity and sensitivity, the CLEC10A Polyclonal Antibody (CAB11859) is a valuable tool for researchers looking to explore the role of CLEC10A in immune cell function and disease pathogenesis. Its use in Western blotting allows for precise and reliable detection of CLEC10A, enabling further investigation into its biological functions and therapeutic potential.
Product Name:
CLEC10A Rabbit Polyclonal Antibody
SKU:
CAB11859
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-180 of human CD301/CLEC10A (NP_878910.1).
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
10462
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD301/CLEC10A Rabbit pAb (CAB11859) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
