The Stromelysin-2 Polyclonal Antibody (CAB3033) is a valuable tool for researchers studying the role of Stromelysin-2 in various cellular processes. Stromelysin-2, also known as matrix metalloproteinase-10 (MMP-10), is a key enzyme involved in matrix remodeling and tissue repair.This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the Stromelysin-2 protein, this antibody enables the detection and analysis of Stromelysin-2 in different cell types and tissues.Stromelysin-2 has been implicated in various pathologies, including cancer metastasis, arthritis, and tissue fibrosis.
Understanding the function and regulation of Stromelysin-2 can provide valuable insights into these diseases and may lead to the development of targeted therapies.Overall, the Stromelysin-2 Polyclonal Antibody is a valuable tool for researchers investigating the role of Stromelysin-2 in both physiological and pathological conditions. Its high specificity and reactivity make it a reliable choice for studies in the fields of cell biology, cancer research, and tissue repair.
Product Name:
MMP10 Rabbit Polyclonal Antibody
SKU:
CAB3033
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 237-476 of human MMP10 (NP_002416.1).
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11.
Purification Method:
Affinity purification
Gene ID:
4319
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MMP10 Rabbit pAb (CAB3033) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
