KLKB1 Rabbit Polyclonal Antibody (CAB13322)
- SKU:
- CAB13322
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | KLKB1 Rabbit Polyclonal Antibody |
SKU: | CAB13322 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 391-500 of KLKB1 (NP_000883.2). |
Sequence: | IVGG TNSS WGEW PWQV SLQV KLTA QRHL CGGS LIGH QWVL TAAH CFDG LPLQ DVWR IYSG ILNL SDIT KDTP FSQI KEII IHQN YKVS EGNH DIAL IKLQ APLN YTEF QK |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | PKK; PPK; KLK3; PKKD; KLKB1 |
Positive Sample: | HT-29,293T,BxPC-3,Mouse liver,Mouse pancreas ,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 71kDa |
Observed MW: | 71kDa |
This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 3818 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |