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Cleaved Gasdermin D (N Terminal) Rabbit Monoclonal Antibody (CAB24059)

SKU:
CAB24059
Product Type:
Antibody
Host Species:
Rabbit
Size:
20uL
Isotype:
IgG
€129
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Description

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Product Name: Cleaved Gasdermin D (N Terminal) Rabbit Monoclonal Antibody
SKU: CAB24059
Size: 20uL
Isotype: IgG
Host Species: Rabbit
Reactivity: Human
Immunogen: A synthetic peptide corresponding to residues surrounding Asp275 of human Gasdermin D(NP_079012.3).
Sequence: NFLTD
Tested Applications: WBELISA
Recommended Dilution: WB: 1:500 - 1:1000
Synonyms: DF5L; DFNA5L; FKSG10; GSDMDC1
Positive Sample: THP-1 treated by LPS and Nigericin
Conjugate: Unconjugated
Cellular Localization: Cytosol, Extracellular region, Extracellular space, NLRP3 inflammasome complex, Nucleoplasm, Plasma membrane
Calculated MW: 53kDa
Observed MW: 31kDa

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Purification Method: Affinity purification
Gene ID: 79792
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product Image Western blot analysis of lysates from THP-1 cells using Cleaved GSDMD (N Terminal) mAb (CAB24059) at 1:1000 dilution. THP-1 cells were treated by LPS and Nigericin. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.
Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020).
Exposure time: 10s.

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