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Cleaved Gasdermin B Polyclonal Antibody (CAB23046)

SKU:
CAB23046
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$155 - $431
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Cleaved Gasdermin B Polyclonal Antibody
SKU:CAB23046
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant protein of human Cleaved Gasdermin B.
Tested Applications:WB ELISA
Recommended Dilution:WB,1:100 - 1:500
Synonyms:GSDML; PP4052; GSDMB-1; PRO2521; Cleaved Gasdermin B
Positive Sample:HT-29
Conjugate:Unconjugated
Calculated MW:18kDa/45kDa/46kDa/47kDa
Observed MW:16kDa

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.

Purification Method:Affinity purification
Gene ID:55876
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from HT-29+NK-92, using Cleaved Gasdermin B Rabbit pAb (CAB23046) at 1:400 dilution.HT-29 and NK-92 cells were treated by IFNγ (50ng/ml) for 8 hours.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 120s.

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