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Cleaved Gasdermin B (C Terminal) Monoclonal Antibody (CAB24342)

SKU:
CAB24342
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €529
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Cleaved Gasdermin B (C Terminal) Monoclonal Antibody
SKU:CAB24342
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:A synthetic peptide corresponding to residues surrounding Ser245 of human Gasdermin B (NP_001159430.1).
Sequence:GKSL G
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:GSDML; PP4052; GSDMB-1; PRO2521; Cleaved Gasdermin B（C Terminal）
Positive Sample:GSDMB-C-6-his, 293T GSDMB stable cells transfected with GZMA
Conjugate:Unconjugated
Cellular Localization:Cytoplasm
Calculated MW:18kDa/45kDa/46kDa/47kDa
Observed MW:16kDa

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.

Purification Method:Affinity purification
Gene ID:55876
Clone Number:ARC63400
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from GSDMB-C-6-his protein, using Cleaved Gasdermin B（C Terminal） Rabbit mAb (CAB24342) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.3s.WB samples for antibody validation are kindly provided by Dr. Feng Shao, NIBS

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