CD97 Monoclonal Antibody (CAB22218)
- SKU:
- CAB22218
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | CD97 Monoclonal Antibody |
SKU: | CAB22218 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-398 of human CD97 (NP_510966.1). |
Sequence: | QDSR GCAR WCPQ NSSC VNAT ACRC NPGF SSFS EIIT TPTE TCDD INEC ATPS KVSC GKFS DCWN TEGS YDCV CSPG YEPV SGAK TFKN ESEN TCQD VDEC QQNP RLCK SYGT CVNT LGSY TCQC LPGF KFIP EDPK VCTD VNEC TSGQ NPCH SSTH CLNN VGSY QCRC RPGW QPIP GSPN GPNN TVCE DVDE CSSG QHQC DSST VCFN TVGS YSCR CRPG WKPR HGIP NNQK DTVC EDMT FSTW TPPP GVHS QTLS RFFD KVQD LGRD SKTS SAEV TIQN VIKL VDEL MEAP GDVE ALAP PVRH LIAT QLLS NLED IMRI LAKS LPKG PFTY ISPS NTEL TLMI QERG DKNV TMGQ SSAR MKLN WAVA AGAE DPGP AV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | CD97; TM7LN1 |
Positive Sample: | U-937 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein, Secreted, extracellular space. |
Calculated MW: | 92kDa |
Observed MW: | 70-85kDa |
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
Purification Method: | Affinity purification |
Gene ID: | 976 |
Clone Number: | ARC55829 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |