The C1R Polyclonal Antibody (CAB15650) is a valuable tool for researchers studying C1R, a cell surface molecule involved in immune response regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the C1R protein, this antibody allows for the detection and analysis of C1R in various cell types, making it an ideal choice for studies in immunology and cancer research.C1R, also known as complement component 1, subcomponent R, plays a critical role in the activation of the complement system, a key component of the immune response.
Dysregulation of the complement system has been implicated in various diseases, including autoimmune disorders, inflammatory conditions, and cancer. Therefore, the ability to study and understand the activity of C1R is of great importance for the development of targeted therapies and interventions in these disease contexts.
Product Name:
C1R Rabbit Polyclonal Antibody
SKU:
CAB15650
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 466-705 of human C1R (NP_001724.3).
This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome.
Purification Method:
Affinity purification
Gene ID:
715
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using C1R Rabbit pAb (CAB15650) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
