CLDN4 Rabbit Polyclonal Antibody (CAB12912)
- SKU:
- CAB12912
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | CLDN4 Rabbit Polyclonal Antibody |
SKU: | CAB12912 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 109-209 of human CLDN4 (NP_001296.1). |
Sequence: | EDES AKAK TMIV AGVV FLLA GLMV IVPV SWTA HNII QDFY NPLV ASGQ KREM GASL YVGW AASG LLLL GGGL LCCN CPPR TDKP YSAK YSAA RSAA ASNY V |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:2000 - 1:4000 IHC-P,1:50 - 1:100 |
Synonyms: | CPER; CPE-R; CPETR; CPETR1; WBSCR8; hCPE-R; CLDN4 |
Positive Sample: | PC-3,MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, tight junction. |
Calculated MW: | 22kDa |
Observed MW: | 18kDa |
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
Purification Method: | Affinity purification |
Gene ID: | 1364 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |