CLCN5 Rabbit Polyclonal Antibody (CAB5707)
- SKU:
- CAB5707
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | CLCN5 Rabbit Polyclonal Antibody |
SKU: | CAB5707 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 637-816 of human CLCN5 (NP_001121370.1). |
Sequence: | YPFL EAKE EFAH KTLA MDVM KPRR NDPL LTVL TQDS MTVE DVET IISE TTYS GFPV VVSR ESQR LVGF VLRR DLII SIEN ARKK QDGV VSTS IIYF TEHS PPLP PYTP PTLK LRNI LDLS PFTV TDLT PMEI VVDI FRKL GLRQ CLVT HNGR LLGI ITKK DVLK HIAQ MANQ DPDS ILFN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | XRN; CLC5; XLRH; CLCK2; ClC-5; DENT1; DENTS; NPHL1; NPHL2; hCIC-K2; CLCN5 |
Positive Sample: | SW480,U-937,HepG2,A673,NCI-H460,Mouse kidney,Mouse ovary,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endosome membrane, Golgi apparatus membrane, Multi-pass membrane protein. |
Calculated MW: | 91kDa |
Observed MW: | 100kDa |
This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1184 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |