CLCN1 Rabbit Polyclonal Antibody (CAB5739)
- SKU:
- CAB5739
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | CLCN1 Rabbit Polyclonal Antibody |
SKU: | CAB5739 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 779-988 of human CLCN1 (NP_000074.3). |
Sequence: | ARPT KKKT TQDS TDLV DNMS PEEI EAWE QEQL SQPV CFDS CCID QSPF QLVE QTTL HKTH TLFS LLGL HLAY VTSM GKLR GVLA LEEL QKAI EGHT KSGV QLRP PLAS FRNT TSTR KSTG APPS SAEN WNLP EDRP GATG TGDV IAAS PETP VPSP SPEP PLSL APGK VEGE LEEL ELVE SPGL EEEL ADIL QGPS LRST DEED EDEL IL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | CLC1; CLCN1 |
Positive Sample: | Mouse skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 109kDa |
Observed MW: | 109kDa |
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1180 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |