CLCN1 Monoclonal Antibody (CAB21237)
- SKU:
- CAB21237
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | CLCN1 Monoclonal Antibody |
SKU: | CAB21237 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 889-988 of human CLCN1 (NP_000074.3). |
Sequence: | NTTS TRKS TGAP PSSA ENWN LPED RPGA TGTG DVIA ASPE TPVP SPSP EPPL SLAP GKVE GELE ELEL VESP GLEE ELAD ILQG PSLR STDE EDED ELIL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:20000 |
Synonyms: | CLC1; CLCN1 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Multi-pass membrane protein. |
Calculated MW: | 109kDa |
Observed MW: | 109kDa |
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1180 |
Clone Number: | ARC52491 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |