Claudin 6 Monoclonal Antibody (CAB24011)
- SKU:
- CAB24011
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
Product Name: | Claudin 6 Monoclonal Antibody |
SKU: | CAB24011 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 119-219 of human Claudin 6(NP_067018.2) |
Sequence: | SGIV FVIS GVLT LIPV CWTA HAII RDFY NPLV AEAQ KREL GASL YLGW AASG LLLL GGGL LCCT CPSG GSQG PSHY MARY STSA PAIS RGPS EYPT KNYV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Positive Sample: | Hep G2,OVCAR-3,Mouse placenta,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | apicolateral plasma membrane, bicellular tight junction, plasma membrane |
Calculated MW: | 23kDa |
Observed MW: | 22kDa |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
Purification Method: | Affinity purification |
Gene ID: | 9074 |
Clone Number: | ARC63026 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |