CLDN3 Rabbit Polyclonal Antibody (CAB11650)
- SKU:
- CAB11650
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | CLDN3 Rabbit Polyclonal Antibody |
SKU: | CAB11650 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 141-220 of human CLDN3 (NP_001297.1). |
Sequence: | TIIR DFYN PVVP EAQK REMG AGLY VGWA AAAL QLLG GALL CCSC PPRE KKYT ATKV VYSA PRST GPGA SLGT GYDR KDYV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | RVP1; HRVP1; C7orf1; CPE-R2; CPETR2; CLDN3 |
Positive Sample: | Mouse liver,Mouse lung,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, tight junction. |
Calculated MW: | 23kDa |
Observed MW: | 27kDa |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.
Purification Method: | Affinity purification |
Gene ID: | 1365 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |