Claudin 1 Polyclonal Antibody (CAB21770)
- SKU:
- CAB21770
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | Claudin 1 Polyclonal Antibody |
SKU: | CAB21770 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 111-211 of human Claudin 1 (NP_066924.1). |
Sequence: | DEVQ KMRM AVIG GAIF LLAG LAIL VATA WYGN RIVQ EFYD PMTP VNAR YEFG QALF TGWA AASL CLLG GALL CCSC PRKT TSYP TPRP YPKP APSS GKDY V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | CLD1; SEMP1; ILVASC; 1 |
Positive Sample: | A-431 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, tight junction. |
Calculated MW: | 23kDa |
Observed MW: | 22kDa |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
Purification Method: | Affinity purification |
Gene ID: | 9076 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |