Clathrin heavy chain Rabbit Monoclonal Antibody (CAB4943)
The Clathrin Heavy Chain Rabbit Monoclonal Antibody (CAB4943) is a powerful tool for researchers studying clathrin-mediated endocytosis and intracellular trafficking processes. This antibody, generated from rabbit hosts, exhibits high specificity and reactivity towards the clathrin heavy chain protein in various species, including human samples.Clathrin is a key protein involved in the formation of coated vesicles, which play a critical role in the internalization and transport of molecules within cells. By targeting the clathrin heavy chain, this antibody enables the precise detection and visualization of clathrin-coated structures in cells, making it an essential reagent for studies in cell biology, neuroscience, and drug delivery research.
The Clathrin Heavy Chain Rabbit Monoclonal Antibody (CAB4943) has been validated for use in a variety of experimental techniques, including immunofluorescence, immunohistochemistry, and Western blotting. Its superior performance and reliability make it an indispensable tool for researchers seeking to unravel the intricate mechanisms of clathrin-mediated processes and their implications in various cellular functions and disease pathways.
Product Name:
Clathrin heavy chain Rabbit Monoclonal Antibody
SKU:
CAB4943
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Clathrin heavy chain (Q00610).
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.
Purification Method:
Affinity purification
Gene ID:
1213
Clone Number:
ARC1228
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Clathrin heavy chain Rabbit mAb (CAB4943) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
