The CLASP1 Polyclonal Antibody (CAB7081) is a valuable tool for researchers studying CLASP1, a microtubule-binding protein that plays important roles in cell division, cell migration, and intracellular transport. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the CLASP1 protein, this antibody enables the detection and analysis of CLASP1 in various cell types, making it an ideal choice for studies in cell biology, cancer research, and neurobiology.
CLASP1 is a key player in microtubule dynamics and organization, influencing processes such as spindle formation during cell division and neurite outgrowth in nerve cells. Dysregulation of CLASP1 has been implicated in diseases such as cancer and neurodevelopmental disorders, making it a promising target for therapeutic interventions. Investigating the function of CLASP1 using this antibody may provide valuable insights into disease mechanisms and potential treatment strategies.
Product Name:
CLASP1 Rabbit Polyclonal Antibody
SKU:
CAB7081
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1389-1538 of human CLASP1 (NP_056097.1).
CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170; MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle (Maiato et al., 2003 [PubMed 12837247]).
Purification Method:
Affinity purification
Gene ID:
23332
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CLASP1 antibody (CAB7081) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
