CKMT2 Rabbit Polyclonal Antibody (CAB8088)
- SKU:
- CAB8088
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | CKMT2 Rabbit Polyclonal Antibody |
SKU: | CAB8088 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-230 of human CKMT2 (NP_001816.2). |
Sequence: | EVRE QPRL FPPS ADYP DLRK HNNC MAEC LTPA IYAK LRNK VTPN GYTL DQCI QTGV DNPG HPFI KTVG MVAG DEES YEVF ADLF DPVI KLRH NGYD PRVM KHTT DLDA SKIT QGQF DEHY VLSS RVRT GRSI RGLS LPPA CTRA ERRE VENV AITA LEGL KGDL AGRY YKLS EMTE QDQQ RLID DHFL FDK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SMTCK; CKMT2 |
Positive Sample: | HeLa,Mouse skeletal muscle,Mouse heart,Mouse diaphragm,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Intermembrane side, Mitochondrion inner membrane, Peripheral membrane protein. |
Calculated MW: | 48kDa |
Observed MW: | 40kDa |
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1160 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |