The CKII Alpha Polyclonal Antibody (CAB17466) is a valuable tool for researchers studying CKII Alpha, a protein kinase involved in various cellular processes, including cell growth, proliferation, and apoptosis. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it suitable for use in Western blot applications.CKII Alpha, also known as casein kinase II alpha, plays a crucial role in cell signaling pathways and has been implicated in cancer progression and other diseases.
By targeting CKII Alpha with this antibody, researchers can investigate its function and potential therapeutic applications in cancer research and drug development.The CKII Alpha Polyclonal Antibody enables the detection and analysis of CKII Alpha protein in a variety of cell types, providing valuable insights into its role in cellular processes and disease mechanisms. Its versatility and reliability make it a valuable asset for studies in molecular biology, cancer biology, and drug discovery.
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. Multiple transcript variants encoding different protein isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1457
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Casein Kinase 2 alpha (CSNK2A1) Rabbit pAb (CAB17466) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
