CKAP5 Rabbit Polyclonal Antibody (CAB8532)
- SKU:
- CAB8532
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Description
Product Name: | CKAP5 Rabbit Polyclonal Antibody |
SKU: | CAB8532 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1763-2032 of human CKAP5 (NP_001008938.1). |
Sequence: | LLHT LCKL KGPK ILDH LTMI DNKN ESEL EAHL CRMM KHSM DQTG SKSD KETE KGAS RIDE KSSK AKVN DFLA EIFK KIGS KENT KEGL AELY EYKK KYSD ADIE PFLK NSSQ FFQS YVER GLRV IEME REGK GRIS TSTG ISPQ MEVT CVPT PTST VSSI GNTN GEEV GPSV YLER LKIL RQRC GLDN TKQD DRPP LTSL LSKP AVPT VASS TDML HSKL SQLR ESRE QHQH SDLD SNQT HSSG TVTS SSST ANID DLKK RLER IKSS RK |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | TOG; MSPS; TOGp; CHTOG; ch-TOG; CKAP5 |
Positive Sample: | HeLa,Jurkat,HepG2,HT-29,Mouse brain,Mouse lung,Mouse liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle pole. |
Calculated MW: | 225kDa |
Observed MW: | 250kDa |
This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 9793 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |