The CKAP2L Polyclonal Antibody (PACO08443) is a valuable tool for research involving the CKAP2L protein, which plays a role in cell division and mitosis. This antibody, raised in rabbits, is highly specific to CKAP2L and is validated for use in various applications, including Western blot and immunohistochemistry.CKAP2L, also known as cytoskeleton-associated protein 2-like, is essential for the proper function of the cytoskeleton during cell division. Understanding the role of CKAP2L is important for research on cell proliferation, growth, and development. The CKAP2L Polyclonal Antibody enables researchers to detect and analyze CKAP2L expression in a variety of cell types, making it a valuable tool for studies in cell biology and cancer research.
By targeting CKAP2L, researchers can gain insights into the mechanisms underlying cell division and potentially identify new therapeutic targets for diseases such as cancer, where dysregulation of cell division processes plays a crucial role. The CKAP2L Polyclonal Antibody is a reliable tool for studying CKAP2L function and its implications for various cellular processes.
cytoskeleton associated protein 2-like;CKAP2L;FLJ40629;MGC39683 ;
UniProt Protein Function:
CKAP2L: Belongs to the CKAP2 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2q13Cellular Component: spindle pole; centrosome; cytoplasmDisease: Filippi Syndrome
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is thought to be a mitotic spindle protein important to neural stem or progenitor cells. Mutations in this gene have been associated with spindle organization defects, including mitotic spindle defects, lagging chromosomes, and chromatin bridges. There is evidence that mutations in this gene are associated with Filippi syndrome, characterized by growth defects, microcephaly, intellectual disability, facial feature defects, and syndactyly. There is a pseudogene of this gene on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
